Introduction
When it comes to allergy relief choosing the right antihistamine can make a significant difference. Xyzal (levocetirizine) and Claritin (loratadine) are two of the most popular over the counter (OTC) allergy medications available today. But which one is better?
This guide provides a detailed comparison between Xyzal and Claritin covering their effectiveness side effects dosage and key differences helping you decide which is best for your needs.
What Are Xyzal and Claritin?
| Feature | Xyzal (Levocetirizine) | Claritin (Loratadine) |
| Drug Class | Second generation antihistamine | Second generation antihistamine |
| Active Ingredient | Levocetirizine Dihydrochloride | Loratadine |
| Availability | OTC and Prescription | OTC |
| Duration of Action | 24 hours | 24 hours |
| Sedation Level | Low to moderate | Minimal to none |
| Common Uses | Seasonal allergies chronic hives skin allergies | Seasonal allergies hay fever skin allergies |
Both medications work by blocking histamine receptors in the body reducing allergy symptoms such as:
- Sneezing
- Runny or stuffy nose
- Itchy watery eyes
- Itchy skin
How Do Xyzal and Claritin Work?
Both medications are H1 receptor antagonists meaning they prevent histamine from binding to receptors thereby stopping allergic reactions.
- Xyzal (Levocetirizine): A purified form of cetirizine (Zyrtec) which provides stronger and faster relief but has a slightly higher risk of drowsiness.
- Claritin (Loratadine): A non drowsy antihistamine with a milder effect but fewer sedative properties.
Effectiveness: Which Works Faster?
| Factor | Xyzal | Claritin |
| Onset Time | 30 60 minutes | 1 3 hours |
| Peak Effect | 1 3 hours | 2 4 hours |
| Duration | 24 hours | 24 hours |
| Strength | More potent | Less potent |
✔ Winner: Xyzal – Works faster and provides stronger relief. However it has a higher chance of causing drowsiness.
✔ Claritin may be better for those looking for a less sedating option with mild allergies.
Side Effects: Which One Has Fewer?
| Side Effect | Xyzal | Claritin |
| Drowsiness | Possible in some users | Rare |
| Dry Mouth | Common | Less common |
| Fatigue | Possible | Rare |
| Headache | Occasionally | Occasionally |
| Nausea | Rare | Rare |
Xyzal Side Effects:
- Some users experience mild drowsiness especially when taken during the day.
- Should be taken at night to reduce fatigue.
Claritin Side Effects:
- Considered a true non drowsy antihistamine.
- Better for daytime use if you need to stay alert.
✔ Winner: Claritin – Causes less drowsiness making it a better option for daily activities.
Dosage Comparison
| Age Group | Xyzal Dosage | Claritin Dosage |
| Adults & Kids (12+ years) | 5 mg once daily (night) | 10 mg once daily |
| Children (6 11 years) | 2.5 mg once daily | 5 mg once daily |
| Children (2 5 years) | 2.5 mg oral solution | 5 mg oral solution |
✔ Xyzal is typically taken at night due to its mild sedative effects. ✔ Claritin can be taken any time of day as it is truly non drowsy.
Who Should Take Xyzal?
✅ If you have moderate to severe allergies and need stronger relief.
✅ If you suffer from chronic hives or skin allergies.
✅ If you don’t mind mild drowsiness and can take it at night.
❌ Avoid if you need to stay alert during the day or are sensitive to drowsiness.
Who Should Take Claritin?
✅ If you have mild to moderate seasonal allergies.
✅ If you need a non drowsy option for daytime use.
✅ If you experience side effects with stronger antihistamines like Xyzal or Zyrtec.
❌ Avoid if you need fast strong relief from severe allergy symptoms.
Cost & Availability
| Factor | Xyzal | Claritin |
| OTC Availability | Yes | Yes |
| Generic Version Available? | Yes | Yes |
| Average Cost (30 Tablets) | $15 $25 | $10 $20 |
✔ Claritin is generally cheaper and more widely available.
✔ Xyzal may be slightly more expensive but some users find it more effective.
Final Verdict: Which One Should You Choose?
| Category | Best Choice |
| Fastest Relief | Xyzal |
| Least Drowsy | Claritin |
| Best for Severe Allergies | Xyzal |
| Best for Mild Allergies | Claritin |
| Best for Chronic Hives | Xyzal |
| Best for Daytime Use | Claritin |
✔ Choose Xyzal if you need stronger fast acting relief and don’t mind mild drowsiness.
✔ Choose Claritin if you want a non drowsy antihistamine for mild seasonal allergies.
Frequently Asked Questions (FAQs)
1. Can I take Xyzal and Claritin together?
No taking both can increase the risk of side effects like drowsiness dry mouth and dizziness.
2. Is Xyzal stronger than Claritin?
Yes Xyzal is a stronger antihistamine and works faster but it may cause more drowsiness than Claritin.
3. Can I take Xyzal or Claritin daily?
Yes both are safe for long term daily use but consult a doctor if you need them regularly.
4. Which is better for pet allergies?
Xyzal is stronger but if you need a non drowsy option Claritin may be better.
Conclusion
Both Xyzal and Claritin are effective allergy medications but your choice depends on your symptoms and lifestyle. If you need stronger relief choose Xyzal. If you prefer a non drowsy option for mild allergies Claritin is a better choice. Always consult a doctor for personalized recommendations.